Dissecting the correlates of N-terminal prohormone brain natriuretic peptide in acute infective endocarditis.

ABSTRACT:

Purpose

To explore the prognostic value and the correlates of NT-proBNP in patients with acute infective endocarditis, a life-threatening disease, with an often unpredictable outcome given by the lack of reliable prognostic parameters.

Methods

We retrospectively studied 337 patients admitted to our centre between January 1, 2006 and September 30, 2020 with available NT-proBNP level at admission. Our analyses were performed considering NT-proBNP as both a categorical variable, using the median value as the cut-off level, and numerical variable. Study end points were in-hospital mortality, cardiac surgery and 1 year survival.

Results

NT-proBNP was an independent predictor of in-hospital mortality (OR 14.9 [95%C.I. 2.46-90.9]; P = .003). Levels below 2926 pg/mL were high

SUBMITTER: Bertolino L 

PROVIDER: S-EPMC9705495 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature