Association between pre-diagnostic dietary copper, zinc, and copper-to-zinc ratio and severity of ovarian cancer.

ABSTRACT:

Background

The impact of dietary trace elements intake on ovarian cancer (OC) severity is unknown.

Objective

We firstly explore the relationship between dietary copper (Cu), zinc (Zn), and copper-to-zinc (Cu/Zn) ratio and severity of OC.

Methods

This cross-sectional study included 701 women from the OC follow-up study between 2015 and 2020. Dietary information was collected by a validated food frequency questionnaire (FFQ). The severity information of OC including age at diagnosis, histological type, International Federation of Gynecology and Obstetrics (FIGO) stage, and histopathologic grade was ascertained from medical records. Logistic regression model was used to estimate the odds ratios (ORs) and 95% confidence intervals (CIs) of aforementioned associations.

R

SUBMITTER: Yin JL 

PROVIDER: S-EPMC9705584 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature