The prognostic role of sex and hemoglobin levels in patients with oral tongue squamous cell carcinoma.

ABSTRACT:

Background

Women and men differ genetically, biologically (sex) and by social construct (gender), possibly impacting on prognostic factors in predicting cancer survival. Hemoglobin levels and immune system activation are players acting in this scenario which could play a role in partly determining prognosis between patients of different sex/gender (S/G). Here, we investigate these factors in patients affected by tongue squamous cell carcinoma.

Methods

This is an observational retrospective cohort study. We collected tongue cancer patients' clinical data, including hemoglobin levels and neutrophil lymphocyte ratio (NLR). Overall survival (OS) and disease-free survival (DFS) were compared between women and men considering confounding and prognostic factors in multivariate Cox

SUBMITTER: Tagliabue M 

PROVIDER: S-EPMC9706199 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature