Network analysis of long non-coding RNA expression profiles in common warts.

ABSTRACT:

Background

Long non-coding RNAs (lncRNAs) have been the subject of considerable attention in recent years due to their role in gene regulation. However, the function of lncRNAs remains poorly understood, especially in the context of infection with low-risk human papillomaviruses (HPVs). To further understanding on this issue, we investigated lncRNA expression in HPV-induced common warts.

Methods

A publicly available high-throughput sequencing dataset for common warts was downloaded from the Gene Expression Omnibus (GEO). lncRNA profiles were generated using the NetworkAnalyst 3.0 workflow, and a list of differentially expressed (DE) lncRNAs in common warts was identified and inputted into the ENCODE, RegNetwork, DisGeNet, and miRNet platforms.

Results

A total of 54 ln

SUBMITTER: Tarkhan AH 

PROVIDER: S-EPMC9706709 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature