Duration of infertility and assisted reproductive outcomes in non-male factor infertility: can use of ICSI turn the tide?

ABSTRACT:

Background

Intracytoplasmic sperm injection (ICSI) is increasingly used among in vitro fertilization (IVF) cycles without male factor infertility. For couples with prolonged infertility duration, the preferred insemination method may vary across laboratories and clinics. We analyzed whether ICSI is effective for non-male factor infertility with long infertility duration.

Methods

Seventeen thousand four hundred seventy-seven IVF/ICSI cycles from women with non-male factor infertility were included, of these 4177 women with infertility duration ≥ 5 years were in the final analysis. Primary outcome was the live birth rate after first embryo transfer. Secondary outcomes were rates of clinical pregnancy and fertilization.

Results

A nonlinear relationship was observed betwe

SUBMITTER: Zhang L 

PROVIDER: S-EPMC9706853 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature