Efficacy and safety of blood derivatives therapy in Alzheimer's disease: a systematic review and meta-analysis.

ABSTRACT:

Background

Blood derivatives therapy is a conventional clinical treatment, while the treatment for Alzheimer's disease (AD) is relatively novel. To provide clinical references for treating AD, this meta-analysis was performed to evaluate the efficacy and safety of blood derivatives therapy on the patients with AD.

Methods

A systematic articles search was performed for eligible studies published up to December 6, 2021 through the PubMed, Embase, Cochrane library, ClinicalTrials.gov , Chinese National Knowledge Infrastructure database, and Wanfang databases. The included articles were screened by using rigorous inclusion and exclusion criteria. Study selection and data-extraction were performed by two authors independently. Random effects model or fixed effects model was used.

SUBMITTER: Fei Z 

PROVIDER: S-EPMC9706869 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature