Immunoinformatics design of multi-epitope peptide-based vaccine against Haemophilus influenzae strain using cell division protein.

ABSTRACT: Haemophilus influenzae is a pathogen that causes invasive bacterial infections in humans. The highest prevalence lies in both young children and adults. Generally, there are no vaccines available that target all the strains of Haemophilus influenzae. Hence, the purpose of this research is to employ bioinformatics and immunoinformatics approaches to design a Multi-Epitope Vaccine candidate employing the pathogenic cell division protein FtsN that specifically combat all the Haemophilus influenzae strains. The current research focuses on developing subunit vaccine in contrast to vaccines generated from the entire pathogen. This will be accomplished by combining multiple bioinformatics and immunoinformatics approaches. As a result, prospective T cells (helper T lymp

SUBMITTER: AlChalabi R 

PROVIDER: S-EPMC9707196 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature