Genotypic characterization of vancomycin-resistant Enterococcus causing urinary tract infection in northern India.

ABSTRACT:

Background & objectives

Infections caused by vancomycin-resistant Enterococci are difficult to treat given the limited therapeutic alternatives. Different gene clusters are known to confer vancomycin resistance. vanA and vanB genes are transferable and are clinically relevant. This cross-sectional study aimed to identify the vancomycin-resistant genotypes in the strains causing urinary tract infection and also to test the in vitro efficacy of linezolid and pristinamycin against the vancomycin-resistant isolates.

Methods

Antimicrobial resistance profile of 118 enterococcal isolates was evaluated. Minimum inhibitory concentration of vancomycin, teicoplanin and high-level gentamicin (HLG) was determined by micro broth dilution. The vancomycin-resistant isolates were tested agai

SUBMITTER: Das AK 

PROVIDER: S-EPMC9707681 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature