Association of Pulmonary Function With Late-Life Cardiac Function and Heart Failure Risk: The ARIC Study.

ABSTRACT: Background Pulmonary and cardiac functions decline with age, but the associations of pulmonary dysfunction with cardiac function and heart failure (HF) risk in late life is not known. We aimed to determine the associations of percent predicted forced vital capacity (ppFVC) and the ratio of forced expired volume in 1 second (FEV₁) to forced vital capacity (FVC; FEV₁/FVC) with cardiac function and incident HF with preserved or reduced ejection fraction in late life. Methods and Results Among 3854 HF-free participants in the ARIC (Atherosclerosis Risk in Communities) cohort study who underwent echocardiography and spirometry at the fifth study visit (2011-2013), associations of FEV₁/FVC and ppFVC with echocardiographic measures, cardiac biomarkers, and risk of

SUBMITTER: Ramalho SHR 

PROVIDER: S-EPMC9707834 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature