Serum amyloid A as a marker to detect sepsis and predict outcome in hospitalized neonatal foals.

ABSTRACT:

Background

Serum amyloid A (SAA) has been reported to hold promise as diagnostic and prognostic marker in foals. This has not been investigated thoroughly.

Objectives

Evaluate admission SAA concentrations as predictor of sepsis and outcome.

Animals

Five hundred and ninety hospitalized foals <14 days old.

Methods

Retrospective multicenter study. Foals were scored with sepsis and survival scores, grouped according to health category (septic, sick but nonseptic, uncertain sepsis status) and outcome; septic foals were further categorized according to severity (normal sepsis, severe sepsis, and septic shock). SAA was compared between groups using Mann-Whitney test and Kruskal-Wallis test. Receiver operating characteristic curves identified optimal SAA cut off values

SUBMITTER: Hoeberg E 

PROVIDER: S-EPMC9708439 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature