Clinical characterization of epileptic seizures in Pomeranians with idiopathic epilepsy or epilepsy of unknown cause.

ABSTRACT:

Background

Focal epileptic motor seizures manifested by limb contraction have been recognized anecdotally in Pomeranians.

Objectives

To investigate clinical features of idiopathic epilepsy (IE) and epilepsy of unknown cause (EUC) in Pomeranians as well as the ADAM23 haplotype frequency previously reported as a common risk haplotype for epilepsy in several breeds of dogs.

Animals

Twenty-eight Pomeranians, including 15 with IE and 13 with EUC. Nine Pomeranians with epilepsy and 8 control Pomeranians were used for ADAM23 risk haplotype analysis.

Methods

Case series study including both retrospectively and prospectively collected cases. The ADAM23 haplotype was determined by direct sequencing of PCR amplicons. Data were analyzed descriptively.

Results

Focal

SUBMITTER: Yu Y 

PROVIDER: S-EPMC9708448 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature