Fecal microbiota of horses with colitis and its association with laminitis and survival during hospitalization.

ABSTRACT:

Background

The association of microbiota with clinical outcomes and the taxa associated with colitis in horses remains generally unknown.

Objectives

Describe the fecal microbiota of horses with colitis and investigate the association of the fecal microbiota with the development of laminitis and survival.

Animals

Thirty-six healthy and 55 colitis horses subdivided into laminitis (n = 15) and non-laminitis (n = 39, 1 horse with chronic laminitis was removed from this comparison) and survivors (n = 27) and nonsurvivors (n = 28).

Methods

Unmatched case-control study. The Illumina MiSeq platform targeting the V4 region of the 16S ribosomal RNA gene was used to assess the microbiota.

Results

The community membership (Jaccard index) and structure (Yue and Clayt

SUBMITTER: Ayoub C 

PROVIDER: S-EPMC9708523 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature