Vitamin C and folate status in hereditary fructose intolerance.

ABSTRACT:

Background

Hereditary fructose intolerance (HFI) is a rare inborn error of fructose metabolism caused by the deficiency of aldolase B. Since treatment consists of a fructose-, sucrose- and sorbitol-restrictive diet for life, patients are at risk of presenting vitamin deficiencies. Although there is no published data on the status of these vitamins in HFI patients, supplementation with vitamin C and folic acid is common. Therefore, the aim of this study was to assess vitamin C and folate status and supplementation practices in a nationwide cohort of HFI patients.

Methods

Vitamin C and folic acid dietary intake, supplementation and circulating levels were assessed in 32 HFI patients and 32 age- and sex-matched healthy controls.

Results

Most of the HFI participants prese

SUBMITTER: Cano A 

PROVIDER: S-EPMC9708598 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature