Left atrial strain determinants and clinical features according to the heart failure stages. New insight from EACVI MASCOT registry.

ABSTRACT: Few studies analyzed left atrial (LA) peak atrial longitudinal strain (PALS) determinants, particularly across heart failure (HF) stages. We aimed to analyze the pathophysiological and clinical PALS correlates in a large multicentric prospective study. This is a multicenter prospective observational study enrolling 745 patients with HF stages. Data included PALS and left ventricular global longitudinal strain (LV-GLS). Exclusion criteria were: valvular prosthesis; atrial fibrillation; cardiac transplantation; poor acoustic window. Median global PALS was 17% [24-32]. 29% of patients were in HF-stage 0/A, 35% in stage-B, and 36% in stage-C. Together with age, the echocardiographic determinants of PALS were LA volume and LV-GLS (overall model R² = 0.50, p < 0.0001). LV-GLS had the

SUBMITTER: Benfari G 

PROVIDER: S-EPMC9708811 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature