Ontology highlight
ABSTRACT:
SUBMITTER: Mazumder AG
PROVIDER: S-EPMC9708923 | biostudies-literature | 2022 Dec
REPOSITORIES: biostudies-literature
Mazumder Arpan G AG Julé Amélie M AM Cullen Paul F PF Sun Daniel D
iScience 20221113 12
Much of what we know about astrocyte form and function is derived from the study of gray matter protoplasmic astrocytes, whereas white matter fibrous astrocytes remain relatively unexplored. Here, we used the ribotag approach to isolate ribosome-associated mRNA and investigated the transcriptome of uninjured fibrous astrocytes from three regions: unmyelinated optic nerve head, myelinated optic nerve proper, and corpus callosum. Astrocytes from each region were transcriptionally distinct and we i ...[more]