Estimation of stillbirths attributable to ambient fine particles in 137 countries.

ABSTRACT: Gestational exposure to ambient fine particles (PM_2.5) increases the risk of stillbirth, but the related disease burden is unknown, particularly in low- and middle-income countries (LMICs). We combine state-of-the-art estimates on stillbirths, and multiple exposure-response functions obtained from previous meta-analyses or derived by a self-matched case-control study in 54 LMICs. 13,870 stillbirths and 32,449 livebirths are extracted from 113 geocoded surveys from the Demographic and Health Surveys. Each stillbirth is compared to livebirth(s) of the same mother using a conditional logit regression. We find that 10-µg/m³ increase of PM_2.5 is associated with an 11.0% (95% confidence interval [CI] 6.4, 15.7) increase in the risk of stillbirth, and the associat

SUBMITTER: Xue T 

PROVIDER: S-EPMC9709081 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature