The earlier the initiation of gonadotropin in poor responders in luteal phase stimulation protocols, the better.

ABSTRACT:

Introduction

Luteal-phase ovarian stimulation has been proved to be feasible for producing competent oocytes/embryos and achieving live births, yet there is no standardized stimulation protocol for luteal-phase ovarian stimulation (LPS). The aim of this study was to explore the optimal timing of gonadotropin initiation in the LPS protocol for poor ovarian responders.

Methods

This was a retrospective cohort study conducted in the reproductive medicine center of a tertiary hospital. A total of 327 poor responders fulfilling Bologna criteria underwent LPS with IVF/ICSI treatment. HMG and letrozole were administrated after ovulation. Patients were stratified into three groups according to the gonadotropin start day: early, early-mid, and mid-late luteal phase. A freeze-all strat

SUBMITTER: Huang J 

PROVIDER: S-EPMC9709114 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature