Neural cue reactivity is not stronger in male than in female patients with alcohol use disorder.

ABSTRACT:

Background

Males consume more alcohol than females, and alcohol use disorder (AUD) is more prevalent in males than females. However, females progress faster to AUD. Sex differences in neural alcohol cue reactivity were previously observed in young social drinkers, indicating a role of hypersensitivity to alcohol-related cues in very early stages of addiction. To our knowledge, this is the first study on patients diagnosed with AUD to test sex differences in neural reactivity to alcohol cues in order to widen previous findings.

Methods

We analyzed data from previous studies, using a well-established functional magnetic resonance imaging (fMRI) paradigm to compare neural reactivity to alcohol cues between 42 female and 124 male patients with AUD (mean age 45 and 46 years) in p

SUBMITTER: Gerhardt S 

PROVIDER: S-EPMC9709253 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature