Quantifying 6D tumor motion and calculating PTV margins during liver stereotactic radiotherapy with fiducial tracking

ABSTRACT:

Objective

Our study aims to estimate intra-fraction six-dimensional (6D) tumor motion with rotational correction and the related correlations between motions of different degrees of freedom (DoF), as well as quantify sufficient anisotropic clinical target volume (CTV) to planning target volume (PTV) margins during stereotactic body radiotherapy (SBRT) of liver cancer with fiducial tracking technique.

Methods

A cohort of 12 patients who were implanted with 3 or 4 golden markers were included in this study, and 495 orthogonal kilovoltage (kV) pairs of images acquired during the first fraction were used to extract the spacial position of each golden marker. Translational and rotational motions of tumor were calculated based on the marker coordinates by using an iterative clo

SUBMITTER: Sun X 

PROVIDER: S-EPMC9709257 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature