Screening for broad-spectrum antimicrobial endophytes from <i>Rosa roxburghii</i> and multi-omic analyses of biosynthetic capacity.

ABSTRACT: Plants with certain medicinal values are a good source for isolating function-specific endophytes. Rosa roxburghii Tratt. has been reported to be a botanical source of antimicrobial compounds, which may represent a promising candidate for screening endophytic fungi with antimicrobial potential. In this study, 54 endophytes were isolated and molecularly identified from R. roxburghii. The preliminary screening using the plate confrontation method resulted in 15 different endophytic strains showing at least one strong inhibition or three or more moderate inhibition against the 12 tested strains. Further re-screening experiments based on the disc diffusion method demonstrated that Epicoccum latusicollum HGUP191049 and Setophoma terrestris HGUP190028 had excellent an

SUBMITTER: Zhang H 

PROVIDER: S-EPMC9709285 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature