Traditional Chinese medicine method of tonifying kidney for hypertension: Clinical evidence and molecular mechanisms.

ABSTRACT: Hypertension is the most common chronic disease. A large amount of evidence showed that traditional Chinese medicine (TCM) method of tonifying kidney (TK) combined with routine treatment is more effective and safer in the treatment of hypertension. This study integrated meta-analysis, data mining, and network pharmacology to explore the efficacy and potential mechanisms of TK in the treatment of hypertension. Meta-analysis was performed to explore the efficacy and safety of TK combined with routine treatment in the treatment of hypertension. Data mining was used to screen the core herbs of the TK. Network pharmacology was used to predict the antihypertensive mechanism of TK core herbs. A total of 18 studies with 2,024 patients were included in this study. Meta-analysis showed that TK combi

SUBMITTER: Wang Q 

PROVIDER: S-EPMC9709460 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature