Metabolism Characteristics of Mycoplasma pneumoniae Infection in Asthmatic Children.

ABSTRACT:

Purpose

Studies have shown that Mycoplasma pneumoniae (Mp) infection can aggravate symptoms in asthmatics. However, the mechanism by which Mp infection exacerbates asthma remains unclear. Metabolomics can help identify the mechanism of Mp aggravating asthma in children, thereby providing more a potential target for improving clinical treatment programs. In this article, we analyzed the metabolic level of patients to explain how Mp aggravates asthma in children.

Methods

We divided the subjects into the asthma, Mp infection, asthma combined with Mp infection and healthy groups. Patients' peripheral blood was collected for metabolic and interaction analysis. Cytokine levels were measured via serum and exhaled breath condensate (EBC).

Results

A total of 150 partici

SUBMITTER: Luo J 

PROVIDER: S-EPMC9709688 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature