Is influenza vaccination associated with nephrotic syndrome relapse in children? A multicenter prospective study.

ABSTRACT:

Background

Prospective research of children receiving heterogeneous vaccines has shown that immunization is not associated with pediatric idiopathic nephrotic syndrome (NS) relapses. However, prospective data concentrating only on influenza (flu) virus vaccines are not available.

Methods

This multicenter prospective study was conducted in children with NS who received inactivated flu vaccines from June 2017 to July 2018. The day of flu vaccination was defined as day 0, and the period between prevaccination and postvaccination days was defined as - X to + Y (period from day - 180 to 0 as the precontrolled period). The primary outcome was the NS relapse rate from day 0 to + 30 as a direct association with vaccination compared with those in the precontrolled period. Exacerbatio

SUBMITTER: Ishimori S 

PROVIDER: S-EPMC9709736 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature