Changes in population immunity against infection and severe disease from SARS-CoV-2 Omicron variants in the United States between December 2021 and November 2022.

ABSTRACT:

Importance

While a substantial fraction of the US population was infected with SARS-CoV-2 during December 2021 - February 2022, the subsequent evolution of population immunity against SARS-CoV-2 Omicron variants reflects the competing influences of waning protection over time and acquisition or restoration of immunity through additional infections and vaccinations.

Objective

To estimate changes in population immunity against infection and severe disease due to circulating SARS-CoV-2 Omicron variants in the United States from December 2021 to November 2022, and to quantify the protection against a potential 2022-2023 winter SARS-CoV-2 wave.

Design setting participants

Bayesian evidence synthesis of reported COVID-19 data (diagnoses, hospitalizations), vaccinations, and

SUBMITTER: Klaassen F 

PROVIDER: S-EPMC9709792 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature