Race Differences in the Associations between Menstrual Cycle Characteristics and Epithelial Ovarian Cancer.

ABSTRACT:

Background

Menstrual cycle characteristics-including age at menarche and cycle length- have been associated with ovarian cancer risk in White women. However, the associations between menstrual cycle characteristics and ovarian cancer risk among Black women have been sparsely studied.

Methods

Using the Ovarian Cancer in Women of African Ancestry (OCWAA) Consortium that includes 1,024 Black and 2,910 White women diagnosed with epithelial ovarian cancer (EOC) and 2,325 Black and 7,549 White matched controls, we investigated associations between menstrual cycle characteristics (age at menarche, age at menstrual regularity, cycle length, and ever missing three periods) and EOC risk by race and menopausal status. Multivariable logistic regression was used to calculate odds ratios

SUBMITTER: Nash R 

PROVIDER: S-EPMC9711941 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature