Dataset Information

Air pollution, climate conditions and risk of hospital admissions for psychotic disorders in U.S. residents.

ABSTRACT:

Background

The physical environmental risk factors for psychotic disorders are poorly understood. This study aimed to examine the associations between exposure to ambient air pollution, climate measures and risk of hospitalization for psychotic disorders and uncover potential disparities by demographic, community factors.

Methods

Using Health Cost and Utilization Project (HCUP) State Inpatient Databases (SIDs), we applied zero-inflated negative binomial regression to obtain relative risks of hospitalization due to psychotic disorders associated with increases in residential exposure to ambient air pollution (fine particulate matter, PM_2.5; nitrogen dioxide, NO₂), temperature and cumulative precipitation. The analysis covered all-age residents in eight U.S. states over the period of 2002-2016. We additionally investigated modification by age, sex and area-level poverty, percent of blacks and Hispanics.

Results

Over the study period and among the covered areas, we identified 1,211,100 admissions due to psychotic disorders. For each interquartile (IQR) increase in exposure to PM_2.5 and NO₂, we observed a relative risk (RR) of 1.11 (95% confidence interval (CI) = 1.09, 1.13) and 1.27 (95% CI = 1.24, 1.31), respectively. For each 1 °C increase of temperature, the RR was 1.03 (95% CI = 1.03, 1.04). Males were more affected by NO₂. Older age residents (≥30 yrs) were more sensitive to PM_2.5 and temperature. Population living in economically disadvantaged areas were more affected by air pollution.

Conclusions

The study suggests that living in areas with higher levels of air pollutants and ambient temperature could contribute to additional risk of inpatient care for individuals with psychotic disorders.

SUBMITTER: Qiu X

PROVIDER: S-EPMC9712244 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature

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Publications

Air pollution, climate conditions and risk of hospital admissions for psychotic disorders in U.S. residents.

Qiu Xinye X Wei Yaguang Y Weisskopf Marc M Spiro Avron A Shi Liuhua L Castro Edgar E Coull Brent B Koutrakis Petros P Schwartz Joel J

Environmental research 20221023 Pt 2

<h4>Background</h4>The physical environmental risk factors for psychotic disorders are poorly understood. This study aimed to examine the associations between exposure to ambient air pollution, climate measures and risk of hospitalization for psychotic disorders and uncover potential disparities by demographic, community factors.<h4>Methods</h4>Using Health Cost and Utilization Project (HCUP) State Inpatient Databases (SIDs), we applied zero-inflated negative binomial regression to obtain relati ...[more]

PMID: 36283440

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Dataset Information

Air pollution, climate conditions and risk of hospital admissions for psychotic disorders in U.S. residents.

Background

Methods

Results

Conclusions

Publications

Air pollution, climate conditions and risk of hospital admissions for psychotic disorders in U.S. residents.

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