Trait related aberrant connectivity in clinically stable patients with schizophrenia: A seed based resting state fMRI study.

ABSTRACT: Aberrant resting-state connectivity within and between the Default Mode Network, the Executive Control Network, and the Salience Network is well-established in schizophrenia. Meta-analyses have identified that bilateral lingual gyrus is as the only region showing hyperactivity in schizophrenia and there are reports of increased connectivity between the lingual gyrus and other brain regions in schizophrenia. It is not clear whether these abnormalities represent state or trait markers of the illness, i.e., if they are only present during the acute phase of the illness (state) or if they reflect a predisposition to schizophrenia (trait). In this study, we used a seed-based functional connectivity analysis to investigate brain networks in schizophrenia patients who are in the stable phase of t

SUBMITTER: Lalousis PA 

PROVIDER: S-EPMC9712324 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature