Change in serial liver stiffness measurement by magnetic resonance elastography and outcomes in NAFLD.

ABSTRACT:

Background and aims

The impact of disease progression in NAFLD on liver outcomes remains poorly understood. We aimed to investigate NAFLD progression using longitudinal liver stiffness measurements (LSM) by serial magnetic resonance elastography (MRE) and the association with liver outcomes.

Approach and results

All adult patients with NAFLD who underwent at least two serial MREs for clinical evaluation at Mayo Clinic, Rochester, between 2007 and 2019 were identified from the institutional database. Progression and regression were defined based on LSM change of 19% above or below 19% of initial LSM, respectively, based on Quantitative Imaging Biomarker Alliance consensus. The association between change in LSM and liver-related outcomes occurring after the last MRE was examin

SUBMITTER: Gidener T 

PROVIDER: S-EPMC9712594 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature