Highly Selective Electrochemical Synthesis of Urea Derivatives Initiated from Oxygen Reduction in Ionic Liquids.

ABSTRACT: The development of more efficient and sustainable methods for synthesizing substituted urea compounds and directly utilizing CO₂ has long been a major focus of synthetic organic chemistry as these compounds serve critical environmental and industrial roles. Herein, we report a green approach to forming the urea compounds directly from CO₂ gas and primary amines, triggered by oxygen electroreduction in ionic liquids (ILs). These reactions were carried out under mild conditions, at very low potentials, and achieved high conversion rates. The fact that O₂ gas was utilized as the sole catalyst in this electrochemical loop, without additional reagents, is a significant milestone for eco-friendly syntheses of C-N compounds and establishes an effective and green C

SUBMITTER: Witherspoon E 

PROVIDER: S-EPMC9713781 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature