Ultrahigh-Resolution Homo- and Heterodecoupled ¹H and TOCSY NMR Experiments.

ABSTRACT: The original homonuclear decoupled (pure shift) experiments provide ultrahigh-resolution ¹H spectra of compounds containing NMR-active heteronuclei of low natural isotopic abundance (e.g., ¹³C or ¹⁵N). In contrast, molecules containing highly abundant heteronuclei (like ³¹P or ¹⁹F) give doublets or a multiple of doublets in their homonuclear decoupled spectra, depending on the number of heteronuclear coupling partners and the magnitude of the respective coupling constants. In these cases, the complex and frequently overlapping signals may hamper the unambiguous assignment of resonances. Here, we present new heteronuclear decoupled (HD) PSYCHE ¹H and TOCSY experiments, which result in simplified spectra with significantly inc

SUBMITTER: Timari I 

PROVIDER: S-EPMC9713892 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature