Risk prediction models of gestational diabetes mellitus before 16 gestational weeks.

ABSTRACT:

Background

Gestational diabetes mellitus (GDM) can lead to adverse maternal and fetal outcomes, and early prevention is particularly important for their health, but there is no widely accepted approach to predict it in the early pregnancy. The aim of the present study is to build and evaluate predictive models for GDM using routine indexes, including maternal clinical characteristics and laboratory biomarkers, before 16 gestational weeks.

Methods

A total of 2895 pregnant women were recruited and maternal clinical characteristics and laboratory biomarkers before 16 weeks of gestation were collected from two hospitals. All participants were randomly stratified into the training cohort and the internal validation cohort by the ratio of 7:3. Using multivariable logistic regressi

SUBMITTER: Wei Y 

PROVIDER: S-EPMC9714187 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature