Bone metastasis risk and prognosis assessment models for kidney cancer based on machine learning.

ABSTRACT:

Background

Bone metastasis is a common adverse event in kidney cancer, often resulting in poor survival. However, tools for predicting KCBM and assessing survival after KCBM have not performed well.

Methods

The study uses machine learning to build models for assessing kidney cancer bone metastasis risk, prognosis, and performance evaluation. We selected 71,414 kidney cancer patients from SEER database between 2010 and 2016. Additionally, 963 patients with kidney cancer from an independent medical center were chosen to validate the performance. In the next step, eight different machine learning methods were applied to develop KCBM diagnosis and prognosis models while the risk factors were identified from univariate and multivariate logistic regression and the prognosis factor

SUBMITTER: Ji L 

PROVIDER: S-EPMC9714267 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature