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Dissection of Besnoitia besnoiti intermediate host life cycle stages: From morphology to gene expression.


ABSTRACT: Cyst-forming Apicomplexa (CFA) of the Sarcocystidae have a ubiquitous presence as pathogens of humans and farm animals transmitted through the food chain between hosts with few notable exceptions. The defining hallmark of this family of obligate intracellular protists consists of their ability to remain for very long periods as infectious tissue cysts in chronically infected intermediate hosts. Nevertheless, each closely related species has evolved unique strategies to maintain distinct reservoirs on global scales and ensuring efficient transmission to definitive hosts as well as between intermediate hosts. Here, we present an in-depth comparative mRNA expression analysis of the tachyzoite and bradyzoite stages of Besnoitia besnoiti strain Lisbon14 isolated from an infected farm animal bas

SUBMITTER: Ramakrishnan C 

PROVIDER: S-EPMC9714946 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature

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