Characteristics associated with decrements in objective measures of physical function in older patients with cancer during chemotherapy.

ABSTRACT:

Purpose

Study purposes were to evaluate for inter-individual variability in the trajectories of three objective measures of physical function (PF) in older patients receiving chemotherapy (n = 112) and determine which characteristics were associated with worse PF.

Methods

Balance, gait speed, and chair-stand test were evaluated at initiation and 1, 3, 6, 9, and 12 months following chemotherapy. Hierarchical linear modeling was used to assess inter-individual variability in the trajectories of the three tests. Demographic, clinical, and symptom characteristics, and levels of cognitive function associated with initial levels and changes over time in each of the tests were determined.

Results

Gait speed and chair-stand tests improved over time. Balance declined until mon

SUBMITTER: Torstveit AH 

PROVIDER: S-EPMC9715479 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature