Is SARS-CoV-2 viral load a predictor of mortality in COVID-19 acute respiratory distress syndrome patients?

ABSTRACT:

Objective

Viral load varies during infection and is higher during the initial stages of disease. Given the importance of the intensive care unit (ICU) in the late stages of COVID-19 infection, analyzing cycle threshold values to detect viral load upon ICU admission can be a clinically valuable tool for identifying patients with the highest mortality risk.

Methods

This was a retrospectively designed study. Patients older than 18 years who tested positive for SARS-CoV-2 PCR and had a PaO₂/FiO₂ ratio <200 were included in the study. The patient population was divided into two groups: survivors and non-survivors.

Results

Two hundred patients were included in the study. In non-survivors, age, relevant ICU admission scores, and procalcitonin levels wer

SUBMITTER: Dogan L 

PROVIDER: S-EPMC9716617 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature