Supplemental Vitamin D and Incident Fractures in Midlife and Older Adults.

ABSTRACT:

Background

Vitamin D supplements are widely recommended for bone health in the general population, but data on whether they prevent fractures have been inconsistent.

Methods

In an ancillary study of the Vitamin D and Omega-3 Trial (VITAL), we tested whether supplemental vitamin D₃ would result in a lower risk of fractures than placebo. VITAL was a two-by-two factorial, randomized, controlled trial that investigated whether supplemental vitamin D₃ (2000 IU per day), n-3 fatty acids (1 g per day), or both would prevent cancer and cardiovascular disease in men 50 years of age or older and women 55 years of age or older in the United States. Participants were not recruited on the basis of vitamin D deficiency, low bone mass, or osteoporosis. Incident fractu

SUBMITTER: LeBoff MS 

PROVIDER: S-EPMC9716639 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature