Preschool development, temperament and genetic liability as early markers of childhood ADHD: A cohort study.

ABSTRACT:

Background

ADHD is associated with multiple adverse outcomes and early identification is important. The present study sets out to identify early markers and developmental characteristics during the first 30 months of life that are associated with ADHD 6 years later.

Methods

9201 participants from the prospective Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort were included. Outcome measures were parent-rated ADHD symptom scores (Strengths and Difficulties Questionnaire, SDQ) and ADHD diagnosis (Development and Wellbeing Assessment, DAWBA) at age 7. Seventeen putative markers were identified from previous literature and included: pre- and peri-natal risk factors, genetic liability (ADHD polygenic risk scores, PRS), early development, temperament scores a

SUBMITTER: Tobarra-Sanchez E 

PROVIDER: S-EPMC9716640 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature