Role of postoperative radiotherapy in resected adenoid cystic carcinoma of the head and neck.

ABSTRACT:

Purpose

Although postoperative radiotherapy (PORT) is demonstrably effective in local control of head and neck adenoid cystic carcinoma (HNACC), its application is controversial and the subset of patients who would benefit most from PORT is unknown. Herein, we analyzed the data of HNACC patients to clarify the role of PORT.

Methods

We retrospectively reviewed 187 patients with nonmetastatic HNACC who underwent surgical resection between 2005 and 2019. The study endpoints were locoregional failure-free survival (LRFFS), progression-free survival (PFS), and overall survival (OS). Subgroup analysis and recursive partitioning analysis (RPA) were performed to identify patients most likely to benefit from PORT.

Results

With a median follow-up of 84.7 months, the 5-year LRFF

SUBMITTER: Choi SH 

PROVIDER: S-EPMC9716721 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature