Histone modifications and DNA methylation act cooperatively in regulating symbiosis genes in the sea anemone Aiptasia.

ABSTRACT:

Background

The symbiotic relationship between cnidarians and dinoflagellates is one of the most widespread endosymbiosis in our oceans and provides the ecological basis of coral reef ecosystems. Although many studies have been undertaken to unravel the molecular mechanisms underlying these symbioses, we still know little about the epigenetic mechanisms that control the transcriptional responses to symbiosis.

Results

Here, we used the model organism Exaiptasia diaphana to study the genome-wide patterns and putative functions of the histone modifications H3K27ac, H3K4me3, H3K9ac, H3K36me3, and H3K27me3 in symbiosis. While we find that their functions are generally conserved, we observed that colocalization of more than one modification and or DNA methylation correlated with si

SUBMITTER: Nawaz K 

PROVIDER: S-EPMC9717517 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature