Mild inflammation persists in the glenohumeral joint of patients with shoulder instability: Cross-sectional study.

ABSTRACT:

Objective

Approximately two-thirds of patients with history of shoulder dislocation may develop osteoarthritis (OA) of the glenohumeral joint. However, the biochemical mechanisms underlying the association between dislocation and OA are largely unknown. This study aimed to investigate macrophage markers and inflammatory cytokine expression associated with shoulder instability (SI) in comparison to rotator cuff tears (RCTs).

Design

This study included 30 patients with SI and 30 patients with RCTs. Synovial membrane samples were harvested from the rotator interval during the arthroscopic anatomical repair for both groups. The localization of tumor necrosis factor-α (TNF-α), interleukin (IL)-1β, and cluster of differentiation (CD) 68 in synovial membranes was determined by immu

SUBMITTER: Muneshige K 

PROVIDER: S-EPMC9718109 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature