The association between preexisting conditions and osteoarthritis development in peripheral joints: A population based nested case-control study.

ABSTRACT:

Aim

To study the risk of receiving a new (incident) osteoarthritis (OA) diagnosis in different joint sites based on conditions diagnosed in the 20 years prior the OA diagnosis.

Methods

We used register data for the entire population of the Skåne region (Sweden) to perform a nested case-control study. The outcome was newly diagnosed (incident) OA in peripheral joints, i.e. knee (ICD-10 code M17), hip (M16) and other joints (M15, M18, M19), diagnosed in 2018 or 2019 in persons aged 45+ years with 20 years of register coverage. For each OA case, we sampled 1 control matched on age (1-year strata), sex and residential area in the year of index date using incidence density sampling. The exposures of interest comprised 50 comorbidities. We used adjusted conditional logistic regres

SUBMITTER: Dell'Isola A 

PROVIDER: S-EPMC9718144 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature