The association between meniscal body extrusion and the development/enlargement of bone marrow lesions on knee MRI in overweight and obese women.

ABSTRACT:

Objective

To determine the association between meniscal body extrusion and bone marrow lesion (BML) development/enlargement in overweight and obese women at high risk of knee osteoarthritis (OA).

Design

We used baseline and 30 months follow-up data of the PROOF study, Netherlands, comprising overweight or obese women aged 50-60 years, free of clinical knee OA. All subjects (n = 395) completed a questionnaire on knee complaints and physical activity, underwent physical examination, radiography, and repeated 1.5 T MRI of both knees. Using the mid-coronal MRI slice, one observer measured tibial plateau width and meniscal body extrusion of both menisci in both knees. BMLs and meniscal damage were read using the semi-quantitative MOAKS scoring system by another observer. The asso

SUBMITTER: Zhang F 

PROVIDER: S-EPMC9718201 | biostudies-literature | 2020 Jan-Feb

REPOSITORIES: biostudies-literature