Insights into the Formations of Host-Guest Complexes Based on the Benzimidazolium Based Ionic Liquids-β-Cyclodextrin Systems.

ABSTRACT: Inclusion complexation is one of the best strategies for developing a controlled release of a toxic drug without unexpected side effects from the very beginning of the administration to the target site. In this study, three benzimidazolium based ionic liquids (ILs) having bromide anion and cation bearing long alkyl chains, hexyl- ([C₆CFBim]Br), octyl- ([C₈CFBim]Br), and decyl- ([C₁₀CFBim]Br) were designed and synthesized as antibacterial drugs. Inclusion complexes (ICs) of studied ILs have been prepared by the combination of β-cyclodextrin (β-CD), considering these conjugations should enhance the benignity of ILs and make them potential candidates for the controlled drug release. Characterizations and structural analysis of studied ICs have been performed b

SUBMITTER: Sarkar B 

PROVIDER: S-EPMC9718304 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature