Modelling the ecological dynamics of mosquito populations with multiple co-circulating Wolbachia strains.

ABSTRACT: Wolbachia intracellular bacteria successfully reduce the transmissibility of arthropod-borne viruses (arboviruses) when introduced into virus-carrying vectors such as mosquitoes. Despite the progress made by introducing Wolbachia bacteria into the Aedes aegypti wild-type population to control arboviral infections, reports suggest that heat-induced loss-of-Wolbachia-infection as a result of climate change may reverse these gains. Novel, supplemental Wolbachia strains that are more resilient to increased temperatures may circumvent these concerns, and could potentially act synergistically with existing variants. In this article, we model the ecological dynamics among three distinct mosquito (sub)populations: a wild-type population free of any Wolbachia infection; an invading population infec

SUBMITTER: Ogunlade ST 

PROVIDER: S-EPMC9718785 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature