GFR Estimation in Potential Living Kidney Donors: Race- and Nonrace-based Equations and Measured GFR

ABSTRACT:

Rationale & Objective

Recent studies evaluated and proposed new race-neutral, creatinine-based glomerular filtration rate (GFR) estimation equations. The performance of these equations in diverse potential living kidney donors requires study.

Study Design

Cross-sectional study.

Setting & Participants

637 potential living kidney donors from one tertiary hospital with serum creatinine concentration measurement and GFR measurement by iohexol plasma clearance between October 2016 and December 2020.

Exposure

Creatinine-based estimation of GFR by Chronic Kidney Disease Epidemiology Collaboration (2009, CKDEPI09; 2021, CKDEPI21) and Modification of Diet in Renal Disease equations with and without inclusion of race coefficient, where applicable.

Outcomes

SUBMITTER: Goodson D 

PROVIDER: S-EPMC9719087 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature