Clinical application of noninvasive chromosomal screening for elective single-blastocyst transfer in frozen-thawed cycles.

ABSTRACT:

Background

The objective of this study was to explore the clinical application of noninvasive chromosomal screening (NICS) for elective single-blastocyst transfer (eSBT) in frozen-thawed cycles.

Methods

This study retrospectively analysed the data of 212 frozen-thawed single-blastocyst transfers performed in our centre from January 2019 to July 2019. The frozen embryos were selected based on morphological grades and placed in preincubation for 6 h after warming. Then spent microdroplet culture media of frozen-thawed blastocysts were harvested and subjected to NICS. The clinical outcomes were evaluated and further stratified analysis were performed, especially different fertilization approaches.

Results

The clinical pregnancy, ongoing pregnancy, and live birth rates in

SUBMITTER: Chen R 

PROVIDER: S-EPMC9719190 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature