Interaction of sex and diabetes on the association between hemoglobin glycation index, hemoglobin A1c and serum uric acid.

ABSTRACT:

Background

Hemoglobin glycation index (HGI), which is calculated by blood glucose and hemoglobin A1c(HbA1c), reflects the individual discrepancy in HbA1c. This study aimed to investigate the association between HGI/HbA1c and serum uric acid(SUA) stratified by sex and diabetes.

Methods

The study recruited 33772 participants who underwent physical examinations between April 2016 and August 2021 in Beijing Chao-Yang Hospital. A random subsample of 3000 subjects was utilized to calculate the formula of HGI and data of the remaining 30772 participants were used for analysis. HGI and HbA1c were categorized according to quartiles (Q1, Q2, Q3, Q4), using Q1 as the reference. We used multiple linear regression and restricted cubic splines for data analysis.

Results

30772 parti

SUBMITTER: Wei Y 

PROVIDER: S-EPMC9719659 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature