Trans-lesional fractional flow reserve gradient as derived from coronary CT improves patient management: ADVANCE registry.

ABSTRACT:

Background

The role of change in fractional flow reserve derived from CT (FFR_CT) across coronary stenoses (ΔFFR_CT) in guiding downstream testing in patients with stable coronary artery disease (CAD) is unknown.

Objectives

To investigate the incremental value of ΔFFR_CT in predicting early revascularization and improving efficiency of catheter laboratory utilization.

Materials

Patients with CAD on coronary CT angiography (CCTA) were enrolled in an international multicenter registry. Stenosis severity was assessed as per CAD-Reporting and Data System (CAD-RADS), and lesion-specific FFR_CT was measured 2 ​cm distal to stenosis. ΔFFR_CT was manually measured as the difference of FFR_CT across visible stenosis.<

SUBMITTER: Takagi H 

PROVIDER: S-EPMC9719736 | biostudies-literature | 2022 Jan-Feb

REPOSITORIES: biostudies-literature