Analysis of benzodiazepines by thermal desorption direct analysis in real time mass spectrometry (TD-DART-MS).

ABSTRACT: One of the several classes of novel psychoactive substances (NPSs) that present analytical challenges for forensic chemists is benzodiazepines. Like other NPS classes, the emergence of new compounds within this class continues, creating a need for the development of new techniques and methods that allow for rapid detection and identification of these compounds in forensics laboratories. This work investigates the use of thermal desorption direct analysis in real time mass spectrometry (TD-DART-MS) as a tool for the rapid and sensitive detection of benzodiazepines. A suite of 19 benzodiazepines were investigated to determine their representative responses. The limits of detection (LODs) for these compounds were found to range from 0.05 ng to 8 ng. Competitive ionization studies highlighted

SUBMITTER: Jones S 

PROVIDER: S-EPMC9720406 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature