The space between us: Modeling spatial heterogeneity in synthetic microbial consortia dynamics.
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ABSTRACT:
SUBMITTER: Godin R
PROVIDER: S-EPMC9720408 | biostudies-literature | 2022 Dec
REPOSITORIES: biostudies-literature
Publications
The space between us: Modeling spatial heterogeneity in synthetic microbial consortia dynamics.
Godin Ryan R Karamched Bhargav R BR Ryan Shawn D SD
Biophysical reports 20221117 4
A central endeavor in bioengineering concerns the construction of multistrain microbial consortia with desired properties. Typically, a gene network is partitioned between strains, and strains communicate via quorum sensing, allowing for complex behaviors. Yet a fundamental question of how emergent spatiotemporal patterning in multistrain microbial consortia affects consortial dynamics is not understood well. Here, we propose a computationally tractable and straightforward modeling framework tha ...[more]
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